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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51a18f8cb671b5794deb12b8151593154b2f35d9fb8b02fe02fe1da8649f3d6d' 
  AND token = 'WBvobxS3SW6YOBbww0XKNYNcbIIeyMsR1uC9h8rgJ9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}