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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b2e7a75b5bf1f13b81c8b3429cba2fa2058a44f35cb5294c3a9d70b2b266c7' 
  AND token = 'JCv0LoLosoKareu5T3CTNeDq9Q6AuwIXtf7t4WqcLDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}