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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a5ea4afd01c89e81c3083455baaa65a9bb868fc9d852b867854ed48f52697fd' 
  AND token = '1Mwniy9e3UqH8mF7Y7bZCl4mGeZVNg3FVyC6G+fhK0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}