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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e86b88c2b8179eabbdcef77cbb28393407e34537de5eb127583c3c5f32a9356' 
  AND token = 't/hNfTRb8NxftJ5GGcR2GTvG1FsVRPk597eTGaF8go0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}