SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b484b0404057626f96d4ffc91e2547e9250da61d310d52cecef24ebaa7758fee' 
  AND token = 'eqo6j/mswa+04AOEzT0w+wBSzbImRtsNGlIsH5kq5sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}