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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8362d6093b646dced5d6453665a32d94a9cd5186a020eb7653e6708a864bab23' 
  AND token = 'p/XYKqhT1gSrIo2H7uH+MoNDrXrnzp35bDRysVhvIg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}