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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f86ba475fd08de5bd98b764e81436b7bfd21047c76f3ea8c2c8b71037c21203' 
  AND token = '383K+4BtrvFF3Oqc9stY+8S3oc/bv0uAZYKl0Ltbp/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}