SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc661db76181e923d5938a5b6dcbac933349661ac223e641b6aa28c9dca63cbf' 
  AND token = 'uoqhMwLDzOvTnH5dXHEamNLDeTq4HGFiAlbtLZYV1BQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}