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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5e9cf1ed501b953508ae8f915991eee1083bd1dd60b88b7cf023d6225935bc9' 
  AND token = '8CmzT2jhaIcPxMY6UIfC/9DrBVsQccDdxl1YC+EQnMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}