SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '336fde103d1bc0834f2be860f22d98e7556e0975c356a9efbe5fa6c6983f9ec8' 
  AND token = 'Tfw1RSGjsMQvGbD3i2L726yWiTqYIEfB9eGu+VP25AM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}