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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e88648232ba078911c0b6d693cc46ebad587432d6a7888e52d8ee11855b5d26' 
  AND token = 'rxDxiaQ7Sf6uQH5Rf/cMrfq0jAji9H9VQ8qQ3w+VDgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}