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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44817daa8057251801c440dade464d2d1f81fd784c60559ca590f23c1cc48d53' 
  AND token = 'D5kp1mpNTH32yvvS8Zp0Lm7kQhhRyFpH+bBSd0rUA9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}