SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c70beeab6892b0c7842288529642c51ebbcd6be1ab2e90d8ea083b8a6070ce' 
  AND token = 'wY+hpQDL4A5MBFfKUMyT8kRmwTWpB3m635RhiPX8yl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}