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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a85d59b2ddb721c0828a98d7a08b9cc19db826f4fe27c337d106bc70bff8ed74' 
  AND token = '+HBbzGJxWncR5sAbWeskxevLJZZvFCixWo4YQqtlyW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}