SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28ee2df7b12326da008ff4d5ca8c86f1c030f3eeff36cef556ed511b681efe0a' 
  AND token = '+jYqAY3gIMMeWBVKyeaBft/FMlqlz7Py/sYISWxc2zY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}