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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6fbecb6181826f6548de12ed36aba11d4bc492270e569e9ab7b2ff3930b12b' 
  AND token = 'eW8ZRxH7gwy3aPUW4/oIx75oXekDH+1M3TrrWv4MQY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}