SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5765673e34913e9d2362bf956899a2f27f2290ac8c0116ef4704c07fb5d45641' 
  AND token = 'SPuTqMp5bAd6A9T5a6uBFNeAwY0zsCQZ6+2yTrbDHEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}