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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4de26369e0a3bb5534d494fe45f1d4bb4cb8bca3d9df474956fea3f942a41890' 
  AND token = 'hQ53t2ZI4E0lM0d8+BeZloJVMsjv1PfOUq1SocFcsW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00072

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}