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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a574bd96e2f5935165c81fcad35eeffb33f1961c043a2a3a2b9d3a02aee39f81' 
  AND token = '27Rf5GCFUMzuWSDaE+if+Q0jfWWFs5JtOwNBB163RIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}