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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e317f46f402e1615b9ce47883073ebd45903a495643075e37cba8e6d559b807' 
  AND token = 'h/bq3LzSL/ojvdnKhQR4FAm4UNQHUSG7wPwATDNU7qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}