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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ca69e1c7b30a611d94cd00e3bffdfd271d3c633fc6b08426a4456aa5be56a8' 
  AND token = 'hiDBnGhr350e/kyAk5so1tjZTehptYzeycql9O+chVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}