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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c8b84441e6ce9b62d44d84e2fe5028dddaf4a2d0e30badb07c264f48c68222c' 
  AND token = '4CAfXZosXtoNOo3lt8BN1/B/rwpAjVTnL8tn5OhhrCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}