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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '758d403defdfd070ec63b35499b69e191c6b22d29973f45648adc531602c4de8' 
  AND token = 'USm+D9PTXZhLagbBNq+ppUTmEokG3f3+6w/F94AL8xU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}