SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c4114aeb4a8320dab5fff9f05e85054312b1efbae5263409c4b7bd831b3309c' 
  AND token = 'VF83uKXima90B3ts3zcEMmHyuJaE0D+219eeWMch7J8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}