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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d6e3fe9becf582b3e4cbaa1c7ee6e2218456fee1ad950b1c326716a3b7b1dbe' 
  AND token = '0mNeDTPxzgLSb3RXmv708qQfi49yzPWzvw2ibb8zDLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}