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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21489ba022b86c7910f50bf711a881741227c16f843412daee206317a53fc610' 
  AND token = 'LVXqTiLpK6Y3dBP16Io/55YU+Tz7E6CCdtlyyozI9Ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}