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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99a9121f4343eea79fccdd48cdb3bb6d99d186207a93fa72e39773c8c4410595' 
  AND token = '8o9BlpmD4n9OB2IQrxV+LKovTEpyWgyNFXPsHCEPfSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}