SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6ea1ff7147e8d57442d46b616c0ce4f91927faea7e910487688dce96e80c397' 
  AND token = '1wheCAlRpiQiBEcJBqQnqDZvaQ1/jWrET9XFkQGiB44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}