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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f08b53eed295579374d3ed56fc077ca588f2781db17a9e48231c888f8d43afd' 
  AND token = '6staG1a6/t2uA+I+Qu8KeXdA9RTowbEjHra3KiEHNRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}