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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c08f3eeda9c71e946070e533ddec065a56a5b641ad49506f1c9a46043172deac' 
  AND token = '+dPQvVsgfZcrp0mDJca+gGnT6tR1f0HF1jl4IjTh1pM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}