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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8814251006d4442d0108290163e8abd442f22f4454cbea9f1757a6762db9b5d5' 
  AND token = 'IPcwDBRfzt7scI/xD0u3xRP2fGsw/0rUiKhW2k9elEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}