SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd29e27db667f52205a76161b793c4462a77a66914b78e69d05d17acef3b978d5' 
  AND token = 'TUVsJDlS4ItazuAUXk4nGfveSCDlVWjEDmqkO9GCz4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}