SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b373043453593e0237bd41b0bb7b1e38cf2f1174ce1b40eb4979691c9b759c4b' 
  AND token = 'CtRglcMiulOsdh42cosO6Q+6JE1wHeKvv0oinBgYAlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}