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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afcd4574406a7df4bf3f88d2d0529a8fd2e2d2972bf9ff88c9658b405d2fd2f4' 
  AND token = 'vbuSSB3MktGxQWCTO0RxTA0MUG+BV3cMLOJlCHuLp5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}