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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fbd7d20eed1194fdf4772f648f8b92df478c5fbbd8fd0bda5dc7d5e21eea94c' 
  AND token = 'mnlDscfCFenKb952T1ZtIl2QPaPHjOKuwRuTJkA4HTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}