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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ee804a6444997518d174477c05c292e327995c285aa892757f2f1a5197b30bc' 
  AND token = 'n2dY7dDf9vn+SyHVE/KUqmP7/SQ5Y7rc95Im3h2vDKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}