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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af0331892e0d9946610e9d1b3e6115d8f8954d6c0a9ae6a432b0de8863ae5880' 
  AND token = 'f4XDrQs03ceXLCqpgeYwfXYtgsl31Q/E0MQ6gRQKCfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}