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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5e8ef32ee5b0f37d141403916dfa0b2fd9af4c73a36ebb553540f2118e91860' 
  AND token = 'LRCzLxao7ySvYFUdKTrVsBZmN3mNtxdnjs7MNxV/hHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}