SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ce1b55b9d117bc1feb2831e423a49dea782c7957fd225f48c6baf710123fca0' 
  AND token = 'bH8gJ+0sXUeD4IfyebOGPu/woR1gR2mmMb/08TPGqWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}