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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aea142bd07c778fab4049968587d261b9f98109be31dbc985ddb8f2d2dc754d8' 
  AND token = 'c46EOMRUHWTQTCC/UfPfDVOveLnJXXOaua9QxA/qp6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}