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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c86d3f5e78e72c67981e8432a53d01630d823dba67b787da12767d3fca86624' 
  AND token = 'nFOXJWMd72mLgod5kmMdHehIYwk2QIcLGmK5pK7fWpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}