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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd395c76f9252c5d7d6f700b9f1990053fa96a89357f448e8c1faa7ff65f9f0f' 
  AND token = 'ghoWc8tSakM6d3XZFUqgmGozzgB/fZMBzToM4Cnf2LA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}