SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a0140a5825cc36b45d01cab828450fa231ec3dad60c80dd503f89a8a205d44' 
  AND token = 'EnDH/geLHQ4ZtxCOEAGC586MuqG7z4ML+vJCzrAhxOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}