SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb3240fca7158d9a9b24aa07795aaca2a49bd7fa8e2e76194b5c8681c0623304' 
  AND token = 'yKY2UMvkmG5e3hTJCytQoNyRotZvbY5YEM/Ek3qxFIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}