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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b035a5191ee934dc69f5c087f1c1c8e0ec235177851f68e31d2ee44eed078044' 
  AND token = 'lO9rmWuzDFXUz4A+F0FVNPTuEvYLaub/1jyWP3KItoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}