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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8adafb7c33a3d03c5ca3f0c8fc5518e70cbe088afba74d543d524bb88b386a' 
  AND token = 'Z+sYpnp/3BLmgqrFvU6luT57tNL2eZw21S+NgbYzCD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}