SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e0c107bcbe2d570700cfa073559da99e5240685a3f82e2c4372c73295e942e0' 
  AND token = 'kWLUDGBvNBJ+98MXcmZHCJy0CfDy5b5GnRuX0ZbJNwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}