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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53dbae72c5fa1ea2e6d84fe5de6e51107e2b4895158e85d646142089edb7f4cf' 
  AND token = '5OxuByDSrQLJmj2g2eugsLeFA/TDq0z6OEUqTlPFv+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}