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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2124ada99d1f11b56354ff9ad0db5cd24b9179f33264d8698f6d925206d68a2' 
  AND token = '0d09mnE8bEI0KVB/lpNMCzGLPQB69PfuoBTp4JMmnp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}