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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ba3a708ecb56e601d908dccc8e646da217c9a275a4c2ee17dc912545a39bb49' 
  AND token = 'H56HJ3hXZVoZGPXqEatg5vWMdcVZ3wiMa6gWzq1y9oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}